Funded by SNF

2018 to date

The full text of the the SNF-funded publications of Prof. Leroux from 2018 on can be found Open Access at the Repository for Publications and Research Data of ETH Zurich and/or at the external page Zurich Open Repository and Archive (ZORA) of the University of Zurich.

2017

January

  • Anna K. Polomska, Marc A. Gauthier and Jean-Christophe Leroux. In vitro and in vivo evaluation of PEGlyated layer-by-layer polyelectrolyte-coated paclitaxel nanocrystals. Small, Weinheim: Wiley, 2016. external page DOI: 10.1002/smll.201602066
    • The content of this article can be found Open Access in the dissertation of Anna K. Polomska.

May

  • Yuhui Gong, Diana Andina, Samsun Nahar, Jean-Christophe Leroux and Marc A. Gauthier. Releasable and traceless PEGylation of arginine-rich antimicrobial peptides. Chemical Science, vol. 8: no. 5, pp. 4082-4086, Cambridge: Royal Society of Chemistry, 2017. external page DOI: 10.1039/c7sc00770a
    • The content of this article can be found Open Access in the dissertation of Yuhui Gong.

2016

February

  • Jessica D. Schulz, Melanie Patt, Sophie Basler, Hajo Kries, Donald Hilvert, Marc A. Gauthier and Jean-Christophe Leroux. Site-specific polymer conjugation stabilizes therapeutic enzymes in the gastrointestinal tract. Advanced Materials, vol. 28: no. 7, pp. 1455-1460, Weinheim: Wiley-VCH, 2016. external page DOI: 10.1002/adma.201504797
    • The content of this article can be found Open Access in the dissertation of Jessica D. Schulz.

2015

November

  • Jessica D. Schulz, Marc A. Gauthier and Jean-Christophe Leroux. Improving oral drug bioavailability with polycations? European journal of pharmaceutics and biopharmaceutics, vol. 97, pp. 427-437, Amsterdam: Elsevier, 2015. external page DOI: 10.1016/j.ejpb.2015.04.025
    • The content of this article can be found Open Access in the dissertation of Jessica D. Schulz.

 

  • Gong Y, Leroux JC, Gauthier MA. Releasable conjugation of polymers to proteins.  (Download PDF (PDF, 732 KB)) Bioconjug Chem. 2015 Jul 15;26(7):1172-81. doi: 10.1021/bc500611k. 

June

  • Forster V, Leroux JC. Injectable nano-antidotes (Nanotidotes) for the treatment of drug
    overdose and poisoning
    (Download PDF (PDF, 408 KB)). Sci Transl Med. 2015 Jun 3; 7(290):290ps14. doi: 10.1126/scitranslmed.3008736.

May

  • Ivarsson ME, Leroux JC and Castagner B. Investigational new treatments for Clostridium difficile infection. (Download PDF (PDF, 199 KB)) Drug Discov Today 2015; 20:602-608.

2014

November

Kathrin Fuhrmann, Marc A. Gauthier, and Jean-Christophe Leroux. Targeting of Injectable Drug Nanocrystals Download (PDF (PDF, 10.5 MB)). Mol. Pharmaceutics, 2014, 11 (6), pp 1762–1771. DOI: 10.1021/mp5001247

Access the final edited and pulished work following external page link

October

Vincent Forster, Rea Debora Signorell, Maurizio Roveri and Jean-Christophe Leroux. Liposome-supported peritoneal dialysis for detoxification of drugs and endogenous metabolites. Sci Transl Med 15 October 2014: Vol. 6, Issue 258, p. 258ra141, DOI: 10.1126/scitranslmed.3009135

Science Translational Medicine: please follow these links for direct access to the information without going through the Member Login screen:
external page Abstract
external page Reprint
external page Full text

January

Simon Matoori, Gregor Fuhrmann, and Jean-Christophe Leroux. Celiac Disease: a Challenging Disease for Pharmaceutical Scientists (Download PDF (PDF, 245 KB)). Pharm Res. 2013 Mar;30(3):619-26. doi: 10.1007/s11095-012-0951-x. Epub 2012 Dec 11.

Access the final edited and pulished work following external page this link

2013

May

Gregor Fuhrmann1, Andrea Grotzky2, Ružica Lukić1, Simon Matoori1, Paola Luciani1, Baozhong Zhang2, Hao Yu2, Peter Walde2, A. Dieter Schlüter2, Marc A. Gauthier1, and Jean-Christophe Leroux1*

Sustained gastrointestinal activity of dendronized polymer–enzyme conjugates (Download PDF (PDF, 1.3 MB))

1Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zurich, Switzerland
2Laboratory of Polymer Chemistry, Department of Materials, ETH Zurich, Switzerland* Corresponding author: Jean-Christophe Leroux

Publication reference: Nature Chemistry 5, 582–589 (2013), doi:10.1038/nchem.1675
Conflict of interest: None to declare
Access the final edited and published work follow this external page link

July

Kathrin Fuhrmann , Anna Połomska , Carmen Aeberli , Bastien Castagner , Marc A. Gauthier , and Jean-Christophe Leroux *

Modular Design of Redox-Responsive Stabilizers for Nanocrystals (Download PDF (PDF, 1.1 MB)) Supporting information (Download PDF (PDF, 3.6 MB))

Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, Swiss Federal Institute of Technology Zurich (ETH Zürich), Wolfgang-Pauli-Straße 10, 8093 Zurich, Switzerland

ACS Nano, 2013, 7 (9), pp 8243–8250
DOI:
10.1021/nn4037317
Publication Date (Web): August 22, 2013
Copyright © 2013 American Chemical Society
Access the final edited and published work follow this external page link

2012

Forster V, Luciani P and Leroux JC.
Download Treatment of calcium channel blocker-induced cardiovascular toxicity with drug scavenging liposomes. (PDF, 658 KB) (PDF, 658 KB)
Biomaterials 2012; 33:3578-3585.

NOTICE: this is the author’s version of a work that was accepted for publication in Biomaterials. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Biomaterials, [VOL 33, ISSUE 13, 2012] DOI: 10.1016/j.biomaterials.2012.01.042.

Access the final edited version and the supplementary data related to external page this article online

2010

Bertrand N, Bouvet C, Moreau P and Leroux JC.

Download Transmembrane pH gradient liposomes to treat cardiovascular drug intoxication. (PDF, 789 KB) ACS Nano 2010, 4:7552-7558 / DOI: 10.1021/nn101924a

This document is the Accepted Manuscript version of a Published Work that appeared in final form in ACS Nano, copyright © American Chemical Society after peer review and technical editing by the publisher.

Access the final edited and published work follow this external page link

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